Compound 3-110-22

CAS No. ——

Compound 3-110-22( —— )

Catalog No. M17085 CAS No. ——

Compound 3-110-22 is a small molecule that inhibits dengue virus (DENV) by binding to its envelope protein E.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Compound 3-110-22
  • Note
    Research use only, not for human use.
  • Brief Description
    Compound 3-110-22 is a small molecule that inhibits dengue virus (DENV) by binding to its envelope protein E.
  • Description
    Compound 3-110-22 is a small molecule that inhibits dengue virus (DENV) by binding to its envelope protein E; inhibits ZIKV PF13-251013-18 with IC90 of 4.0 uM, interacts with recombinant, soluble ZIKV E (ZIKV sE) in biolayer interferometry experiments with a KD of 2.1 uM; inhibits other flavivirus pathogens, inhibits DENV fusion by targeting E; also inhibits West Nile reporter virus with IC50 of 2.9 uM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Filovirus
  • Recptor
    Filovirus
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    ——
  • Formula Weight
    357.292
  • Molecular Formula
    C18H10F3N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    (E)-2-(benzofuran-2-yl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetohydrazonoyl cyanide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. de Wispelaere M, et al. Cell Chem Biol. 2018 Jun 1. pii: S2451-9456(18)30182-X.
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