Compound 3-110-22
CAS No. ——
Compound 3-110-22( —— )
Catalog No. M17085 CAS No. ——
Compound 3-110-22 is a small molecule that inhibits dengue virus (DENV) by binding to its envelope protein E.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameCompound 3-110-22
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NoteResearch use only, not for human use.
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Brief DescriptionCompound 3-110-22 is a small molecule that inhibits dengue virus (DENV) by binding to its envelope protein E.
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DescriptionCompound 3-110-22 is a small molecule that inhibits dengue virus (DENV) by binding to its envelope protein E; inhibits ZIKV PF13-251013-18 with IC90 of 4.0 uM, interacts with recombinant, soluble ZIKV E (ZIKV sE) in biolayer interferometry experiments with a KD of 2.1 uM; inhibits other flavivirus pathogens, inhibits DENV fusion by targeting E; also inhibits West Nile reporter virus with IC50 of 2.9 uM.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMicrobiology/Virology
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TargetFilovirus
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RecptorFilovirus
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight357.292
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Molecular FormulaC18H10F3N3O2
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(E)-2-(benzofuran-2-yl)-2-oxo-N-(3-(trifluoromethyl)phenyl)acetohydrazonoyl cyanide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. de Wispelaere M, et al. Cell Chem Biol. 2018 Jun 1. pii: S2451-9456(18)30182-X.
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